Anti-GFAP+1
| Species Reactivity | Key Applications | Host | Format | Antibody Type |
|---|---|---|---|---|
| H | WB, IH | Rabbit | Serum | Polyclonal Antibody |
UniProt Number:
UniProt Summary
FUNCTION: SwissProt: P14136 # GFAP, a class-III intermediate filament, is a cell- specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander di ... see more »
SIZE: 432 amino acids; 49880 Da
SUBUNIT: Isoform 3 interacts with N-terminus of PSEN1.
SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with intermediate filaments.
DISEASE: SwissProt: P14136 # Defects in GFAP are a cause of Alexander di ... see more »
Entrez Gene Number:
Entrez Gene Summary
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant has been described, but its full length sequence has not been determined.
Description:
Anti-GFAP+1
Trade Name:
Upstate (Millipore)
Key Applications:
- Western Blotting
- Immunohistochemistry
Species Reactivity:
Human
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Antibody Sub-Category:
Neurodegenerative Diseases
Specificity:
GFAP+1
Purification Method:
serum
Antibody Category:
Neuroscience
Gene Symbol:
- GFAP
- FLJ45472
Format:
Serum
Molecular Weight:
50kDa
Presentation:
antiserum containing 0.05% sodium azide and 30% glycerol.
Isotype:
IgG
Immunogen:
synthetic peptide corresponding to a neo-C-terminus generated as a result of alternative splicing of the human GFAP mRNA (Hol et al, 2003)
Quality Assurance:
Routinely evaluated by immunoblot of GFAP+1 protein
Antibody Type:
Polyclonal Antibody
Storage Conditions:
1 year at -20°C
Host:
Rabbit